4-Amino-1-methylpiperidine → HCID 11713492, compound

HRID 2356948Notes

Reaction equation

HRID 2356948 reaction equation
[CH3:1][C:2]1([CH3:32])[C:6](=[O:7])[N:5]([C:8]2[CH:9]=[CH:10][C:11]([O:18][CH3:19])=[C:12]([CH:17]=2)[O:13][CH2:14][CH:15]=O)[C:4](=[O:20])[N:3]1[CH2:21][C:22]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[N:25]=[CH:24][CH:23]=1.[NH2:33][CH:34]1[CH2:39][CH2:38][N:37]([CH3:40])[CH2:36][CH2:35]1>>[CH3:19][O:18][C:11]1[CH:10]=[CH:9][C:8]([N:5]2[C:6](=[O:7])[C:2]([CH3:1])([CH3:32])[N:3]([CH2:21][C:22]3[C:31]4[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=4)[N:25]=[CH:24][CH:23]=3)[C:4]2=[O:20])=[CH:17][C:12]=1[O:13][CH2:14][CH2:15][NH:33][CH:34]1[CH2:39][CH2:38][N:37]([CH3:40])[CH2:36][CH2:35]1

Participants

3

Reactant 2

HCID 27375314-Amino-1-methylpiperidineHCID 86617223HCID 86617223, compound

Product 1

HCID 11713492HCID 11713492, compound

Procedure

The title compound was prepared in analogy to example 51e by using 100 mg [5-(4,4-dimethyl-2,5-dioxo-3-quinolin-4-ylmethyl-imidazolidin-1-yl)-2-methoxy-phenoxy]-acetaldehyde as starting material and 4-amino-1-methylpiperidine instead of morpholine.

Sources & evidence

ORD record
ord-d37d1ed2e60648a5bf9ca4c25f857a68
Source dataset
uspto-grants-2010_07
Patent number
US07759379B2

Reaction notes

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