反应详情

100 mg (0.27 mmol) of 3-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-5,5-dimethyl-1-pyridin-4-ylmethylimidazolidine-2,4-dione were initially charged in 1 ml of pyridine, and 88 mg (0.41 mmol) of 2-pyridylsulphonyl chloride hydrochloride were added. For workup, the mixture was concentrated fully and the residue purified by flash chromatography (100 g of silica gel/95:5 CH2Cl1:CH30H).

1. concentrationFor workup, the mixture was concentrated fully
2. customthe residue purified by flash chromatography (100 g of silica gel/95:5 CH2Cl1:CH30H)