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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2356975Generated: October 31, 2026

HCID 68458911, compound → HCID 58668697, compound

https://huagongshe.com/reaction/2356975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68458911HCID 68458911—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 58668697HCID 5866869799.2%

Reaction Steps

(7-Benzenesulfonyl-chroman-4-ylidene)-acetonitrile (395 mg, 1.27 mmol) was dissolved in 4 mL EtOAc and placed in a Parr flask containing 40 g of Pd (10% wt) on carbon. The flask was sealed and shaken overnight under 50 psi of hydrogen. The Pd/C was removed by filtration and the solvent was evaporated under reduced pressure to afford 397 mg (1.26 mmol, 99%) of (7-benzenesulfonyl-chroman-4-yl)-acetonitrile. MS: 314 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07759389B2
Source datasetuspto-grants-2010_07
ORD IDord-c567ed085aee45ea9037c67108d95e6e
Source noteuspto-grants-2010_07