Hydroxylamine → HCID 86607607, compound

Participants

Reaction Steps

A solution of 4-chloro-2-fluoro-3-iodobenzaldehyde (4.60 g, 16 mmol) in ethanol (25 mL) at RT was treated with hydroxylamine (4.5 mL, 162 mmol) and the reaction was to stir for 12 h. The volatiles were removed and the residue was treated with water (25 mL), and extracted with ethyl acetate (3×25 mL). The combined ethyl acetate layers were dried over magnesium sulfate and concentrated to provide an off white solid 4-chloro-2-fluoro-3-iodobenzaldehyde oxime. MS (ESI, pos.ion) m/z: 299.9 (M+1)

Provenance & Evidence