HCID 86741284, compound → HCID 86741286, compound

Participants

Reaction Steps

A mixture of 4-nitrobenzyl 2-diazo-4-[(2R,3R)-3-(1-methoxy-1-methylethyl)-4-oxoazetidin-2-yl]-3-oxobutanoate (707 mg) and rhodium (II) acetate (ca. 5 mg) in benzene (20 ml) was refluxed for 30 minutes. After cooling to ambient temperature, the mixture was filtered through cellulose powder. The filtrate was evaporated to give 4-nitrobenzyl (2R,5R,6R)-3,7-dioxo-6-(1-methoxy-1-methylethyl)-1-azabicyclo[3.2.0]heptane-2-carboxylate (680 mg).

Provenance & Evidence