Toluene → HCID 86607612, compound

Participants

Reaction Steps

(R)-1-Allyl 2-ethyl 5-oxopyrrolidine-1,2-dicarboxylate (9.1 g, 38 mmol) was dissolved in dichloromethane (100 mL) and cooled to 0° C. before trimethylaluminum—2 M in toluene (94 mL, 190 mmol) was added. The reaction was stirred at ambient temperature for 16 h. The reaction mixture was quenched with a minimal amount of ammonium chloride (saturated, aqueous) to form a white solid, which was filtered off to give crude product. The crude was purified by chromatography to obtain the title compound. Found MS (ES+): 258(M+H)+.

Provenance & Evidence