1,6-Dichlorophthalazine → HCID 68455659, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (S)-tetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one (1.42 g, 10.000 mmol), 1,6-dichlorophthalazine (1.47 g, 7.39 mmol) and N,N-DIPEA (5.00 mL, 30.0 mmol) in 12 mL DMF was heated at 135° C. The crude material was purified by flash chromatography eluting with 2 M NH3 in MeOH/CH2Cl2 (0:1→3:97) to give 1.85 g of a brown oil. MS m/z: 305.1, 307.1 [M+1].

Provenance & Evidence