HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 235779Generated: October 29, 2026
Citric Acid → 3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine
https://huagongshe.com/reaction/235779
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 3-(1-Methylpyrrolidin-2-yl)pyridine | HCID 942 | — |
| Product | 3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine | HCID 409 | — |
Reaction Steps
500 g of nicotine (3.08 mol) are slowly added dropwise to an equimolar 30% hydrogen peroxide solution containing 5.9 g of citric acid (30.8 mmol), the temperature being maintained below 90° C. After the addition has ended, the mixture is heated at 80° C. for 5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04641667 |
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| Source dataset | uspto-grants-1987_02 |
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| ORD ID | ord-a8960d59cebc469091e2f3f196126c97 |
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| Source note | uspto-grants-1987_02 |
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