HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetic acid, alpha-bromo-, methyl ester → {(1S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-1H-isoquinolin-2-yl}-phenyl-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetic acid, alpha-bromo-, methyl ester | HCID 137806 | — |
| Reactant | (S)-6,7-Dimethoxy-1-(4-(trifluoromethyl)phenethyl)-1,2,3,4-tetrahydroisoquinoline | HCID 44133419 | — |
| Product | {(1S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-1H-isoquinolin-2-yl}-phenyl-acetic acid methyl ester | HCID 59389634 | — |
Reaction Steps
This compound is prepared by reaction of (1S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydroisoquinoline with α-bromo-phenyl-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763638B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-adafd70019e648fbbe84d57fef4d0132 |
| Source note | uspto-grants-2010_07 |