HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropane → 4-[2-Fluoro-3-(methylsulfonyl)phenyl]-1-isopropyl-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-[2-Fluoro-3-(methylsulfonyl)phenyl]piperidine | HCID 57448038 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-[2-Fluoro-3-(methylsulfonyl)phenyl]-1-isopropyl-piperidine | HCID 67532142 | — |
Reaction Steps
Preparation according to Example 1: 4-[2-fluoro-3-(methylsulfonyl)-phenyl]-piperidine (0.02 g, 0.078 mmol), acetonitrile (2 ml), potassium carbonate (0.02 g, 0.14 mmol), 2-bromopropane (0.008 ml, 0.082 mmol). MS m/z (relative intensity, 70 eV) 299 (M+, 3), 285 (15), 284 (bp), 205 (6) 133 (4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763639B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-b473f42c7dd24b028da6599e5c9e0a9d |
| Source note | uspto-grants-2010_07 |