HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 1-[3-(1-Allylpiperidin-4-YL)-2-fluorophenyl]-2,2,2-trifluoroethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 67532664 | HCID 67532664 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-[3-(1-Allylpiperidin-4-YL)-2-fluorophenyl]-2,2,2-trifluoroethanone | HCID 67533177 | — |
Reaction Steps
Preparation according to Example 1: 2,2,2-trifluoro-1-(2-fluoro-3-piperidin-4-ylphenyl)ethanone (0.01 g), acetonitrile (2 ml), potassium carbonate (0.01 g) and allylbromide (0.01 g). MS m/z (rel. intensity, 70 eV) 315 (M+, 60), 314 (82), 288 (bp), 286 (31), 96 (36).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763639B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-7d54612048c24dfcaab35814f4770d58 |
| Source note | uspto-grants-2010_07 |