Pyridinium chloride → HCID 57448052, compound

HRID 2358138Notes

Reaction equation

HRID 2358138 reaction equation
C[O:2][C:3]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1.Cl.N1C=CC=CC=1>>[NH:16]1[CH2:17][CH2:18][CH:13]([C:4]2[CH:5]=[CH:6][CH:7]=[C:8]([C:9]([F:11])([F:12])[F:10])[C:3]=2[OH:2])[CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 57448040HCID 57448040, compound

Product 1

HCID 57448052HCID 57448052, compound

Procedure

Preparation according to Example 29: 4-[2-methoxy-3-(trifluoromethyl)phenyl]piperidine (0.07 g, 0.27 mmol), pyridine hydrochloride (0.4 g). Yield: 0.05 g. MS m/z (relative intensity, 70 eV) 245 (M+, bp), 226 (21), 167 (25), 140 (15), 56 (42).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-1846280ef7c146ebbceab05e280f2c13
Source dataset
uspto-grants-2010_07
Patent number
US07763639B2

Reaction notes

Loading…