HCID 9992682, compound → HCID 86631768, compound

Participants

Reaction Steps

Analogously to example 12, tert-butyl 1-(2′-formyl-6′-methoxybenzyl)-3-methoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylate was reacted with tert-butyl-(3-methoxymethoxypent-4-ynyloxy)dimethylsilane. After work-up by column chromatography on silica gel (CHCl3/EA 95:5), the addition product tert-butyl 6″-(tert-butyldimethylsilanyloxy)-1″-hydroxy-4″-methoxymethoxyhex-2″-ynyl]-6′-methoxybenzyl}-3-methoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid could be obtained in the form of a yellow oil (230 mg, 0.31 mmol, 75%).

Provenance & Evidence