HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 131727257, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | HCID 59837307 | HCID 59837307 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 131727257 | HCID 131727257 | — |
Reaction Steps
The compound of Example 175 was optically resolved by HPLC (Chiralpak AD, hexane:ethanol=85:15, wavelength=UV 254 nm, flow rate=3 mL/min). A compound with an optical rotation of [α]25.3D +4.6° (C=1.0, chloroform) and a compound with an optical rotation of ([α]25.6D −2.2° (C=1.0, chloroform) were obtained from the first elution fraction and the second elution fraction, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763752B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-0078c8354e034655825005ff2d5923b1 |
| Source note | uspto-grants-2010_07 |