HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 5-Chloro-2-ethyl-1,8-naphthyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178435554 | HCID 178435554 | — |
| Product | 5-Chloro-2-ethyl-1,8-naphthyridine | HCID 67251203 | 83% |
Reaction Steps
The product from Example 3e (200 mg, 1.14 mmol) was treated with POCl3 following the procedure from Example 1d giving the title compound as a brown solid (183 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763731B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-b378632bf7dc4f7cb9e31480bc0c5d4b |
| Source note | uspto-grants-2010_07 |