HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 4-Chloro-2,7-dimethyl-[1,8]naphthyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2,7-Dimethyl-1,8-naphthyridin-4-ol | HCID 10678817 | — |
| Product | 4-Chloro-2,7-dimethyl-[1,8]naphthyridine | HCID 11206333 | — |
Reaction Steps
The product from Example 14a (500 mg, 2.87 mmol) was reacted with 10 mL of POCl3 for 2 h following the procedure from Example 1d giving the title compound, which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763731B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-443155a58a9c4af0b5e3f186a747dda1 |
| Source note | uspto-grants-2010_07 |