Stannous Chloride → 5-METHYL-2-PHENOXYANILINE

HRID 2358586Notes

Reaction equation

HRID 2358586 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[C:4]([N+:15]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)=[C:4]([NH2:15])[CH:3]=1

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 10353762HCID 10353762, compound

Product 1

HCID 103978675-METHYL-2-PHENOXYANILINEYield 93%

Procedure

The product from Example 41a (884 mg, 3.86 mmol) was treated with SnCl2 (3.5 g, 19.0 mmol) for 24 h following the procedure from Example 1f giving the title compound as a yellow oil (710 mg, 93%).

Sources & evidence

ORD record
ord-a0f07d5a26574a27a1bd2718fb77e5e2
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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