4-Methylbenzenethiol → 4-Methyl-2-nitro-1-p-tolylsulfanyl-benzene

HRID 2358596Notes

Reaction equation

HRID 2358596 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5](OS(C(F)(F)F)(=O)=O)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1.[CH3:19][C:20]1[CH:25]=[CH:24][C:23]([SH:26])=[CH:22][CH:21]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:26][C:23]2[CH:24]=[CH:25][C:20]([CH3:19])=[CH:21][CH:22]=2)=[C:4]([N+:16]([O-:18])=[O:17])[CH:3]=1

Participants

3

Reactant 2

HCID 78114-MethylbenzenethiolHCID 713468894-Methyl-2-nitrophenyl trifluoromethanesulfonate

Product 1

HCID 684576704-Methyl-2-nitro-1-p-tolylsulfanyl-benzene

Procedure

The product from Example 4a (5.00 g, 17.53 mmol) was reacted with 4-methylthiophenol (2.17 g, 17.53 mmol) in place of thiophenol following the procedure from Example 1e for 18 h giving the crude title compound which was purified by silica gel column chromatography eluting with 5% EtOAc/hexane providing a solid (3.53 g, 78%).

Sources & evidence

ORD record
ord-684f7f3363c94935959883043de42a0f
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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