4-Fluorothiophenol → 1-(4-Fluoro-phenylsulfanyl)-4-methyl-2-nitro-benzene

Participants

Reaction Steps

The product from Example 4a (5.00 g, 17.53 mmol) was reacted with 4-fluorothiophenol (2.24 g, 17.53 mmol) in place of thiophenol following the procedure from Example 1e for 18 h giving the crude title compound which was purified by silica gel column chromatography eluting with 5% EtOAc hexane providing a solid (3.39 g, 74%).

Provenance & Evidence