Potassium Carbonate → 3-(4-Methyl-2-nitro-phenylsulfanyl)-phenylamine

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	3-Aminothiophenol	HCID 31577	—
Reactant	4-Methyl-2-nitrophenyl trifluoromethanesulfonate	HCID 71346889	—
Solvent	Water	HCID 962	—
Solvent	Dimethylformamide	HCID 6228	—
Product	3-(4-Methyl-2-nitro-phenylsulfanyl)-phenylamine	HCID 68457917	—

Reaction Conditions

Temperature	10 °C

Reaction Steps

The product from Example 4a (1.00 g, 3.51 mmol) and 3-Amino-benzenethiol (658 mg, 5.26 mmol) were dissolved in DMF to which was added K2CO3 (848 mg, 6.14 mmol). The reaction mixture was then heated to 10° C. for 16 hrs. Reaction mixture was then cooled to room temperature, diluted with water and extracted with ethyl acetate providing the title compound (650 mg, 71%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07763731B2
Source dataset	uspto-grants-2010_07
ORD ID	ord-32c5efcd8b4a43468ae3225ab42929ce
Source note	uspto-grants-2010_07