Ethanol → HCID 68458795, compound

Participants

Reaction Steps

The product from Example 2g as a 3.15M solution in ethanol (0.08 mL, 0.25 mmol) was reacted with the product from Example 115b (0.061 g, 0.25 mmol) for 18.5 h following the procedure from Example 1g giving the crude title compound which was purified by HPLC with TFA providing the product as a trifluoroacetic acid salt (0.0195 g, 14%). 1H NMR (300 MHz, DMSO-d6) δ ppm: 0.98 (t, J=7.35 Hz, 3 H) 1.75-1.93 (m, 2 H) 2.31-2.42 (s, 3 H) 2.91-3.08 (m, 2 H) 4.42 (s, 2 H) 6.30 (d, J=6.99 Hz, 1 H) 7.11-7.42 (m, 7 H) 7.81 (d, J=8.46 Hz, 1 H) 8.39 (d, J=6.99 Hz, 1 H) 8.98 (d, J=8.82 Hz, 1 H) 11.01 (s, 1 H); MS (ESI+) m/z 416.2 (M+H)+, (ESI−) m/z 414.3 (M−H)−.

Provenance & Evidence