HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → 4-(4-chloro-2-nitrophenoxy)-N,N-diethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 4-(4-Chloro-2-nitrophenoxy)benzoyl chloride | HCID 86615494 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-chloro-2-nitrophenoxy)-N,N-diethylbenzamide | HCID 51149700 | — |
Reaction Steps
The compound from Example 126c (1.0 g, 3.2 mmol) in CH2Cl2 was added to a mixture of diethylamine (469 mg, 6.41 mmol) in CH2Cl2. Mixture was stirred for 12 hours. Mixture was concentrated under vacuum giving the title compound, which was purified by silica gel column chromatography eluting with 50% EtOAc/hexane giving a yellow oil (1.1 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763731B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-5aabfdb134934edaaa2aea291ad956e0 |
| Source note | uspto-grants-2010_07 |