HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 68460694, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-(4-Chloro-2-nitrophenoxy)benzoyl chloride | HCID 86615494 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68460694 | HCID 68460694 | 50% |
Reaction Steps
The product from Example 126c (225 mg, 0.72 mmol) was reacted with methylamine (1.0 mL, 2.0 mmol) in THF (20 mL) at room temperature. The THF was removed under reduced pressure. The crude residue was purified by flash chromatography eluting with hexanes/ethyl acetate (30:70) to give the title compound (110 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07763731B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-e02af5787818434fa3a92769ca871acc |
| Source note | uspto-grants-2010_07 |