Sodium borohydride → HCID 43506274, compound

Participants

Reaction Steps

The product from Example 164a (0.7 g, 2.4 mmol) was added to ethanol (30 mL) and sodium borohydride (115 g, 3.11 mmol) was added portion wise. The reaction was stirred for 1 h and then the excess sodium borohydride was destroyed by drop wise addition of acetic acid. The reaction was poured onto ice/water and extracted with ethyl acetate. The organic phase washed with water, brine, and dried over sodium sulfate, filtered and concentrated under vacuum giving the title compound (0.634 g, 90%).

Provenance & Evidence