Stannous Chloride → 3-(2-Amino-4-chloro-phenoxy)-benzamide

HRID 2358751Notes

Reaction equation

HRID 2358751 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=2)[C:10]([NH2:12])=[O:11])=[C:4]([N+:18]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:18][C:4]1[CH:3]=[C:2]([Cl:1])[CH:17]=[CH:16][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([NH2:12])=[O:11]

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 684618453-(4-Chloro-2-nitro-phenoxy)-benzamide

Product 1

HCID 284018643-(2-Amino-4-chloro-phenoxy)-benzamideYield 120.2%

Procedure

The product from Example 171a (0.56 g, 1.9 mmol) was reacted with SnCl2 following the procedure described in Example 1f to give the title compound (0.60 g, 83%).

Sources & evidence

ORD record
ord-7e41eb6ca5f6497db501d3790f072b78
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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