Dimethylamine → HCID 52172897, compound

Participants

Reaction Steps

The product from Example 181c (1.0 g, 3.4 mmol) was added to THF (25 mL) and dimethylamine (0.31 g, g, 6.8 mmol) was added. The reaction was stirred at room temperature for 16 h. The reaction was poured onto ice/water and extracted with ethyl acetate. The organic phase was washed with 5% HCl, water, brine, and dried over sodium sulfate, filtered and concentrated under vacuum giving the title compound (0.90 g, 87%).

Provenance & Evidence