Stannous Chloride → HCID 68458796, compound

HRID 2358767Notes

Reaction equation

HRID 2358767 reaction equation
[F:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=2)[C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[C:4]([N+:20]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:20][C:4]1[CH:3]=[C:2]([F:1])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=1)[C:10]([N:12]([CH3:13])[CH3:14])=[O:11]

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 52172897HCID 52172897, compound

Product 1

HCID 68458796HCID 68458796, compoundYield 94.4%

Procedure

The product from Example 181d (1.1 g, 3.4 mmol) was reduced with SnCl2 as described in Example 1f to give the title compound (0.88 g, 88%).

Sources & evidence

ORD record
ord-eef7a09481f3410bb9b565c7e94291d2
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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