Methanol → HCID 13392287, compound

HRID 235877Notes

Reaction equation

HRID 235877 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([C:19]3[O:20][CH:21]=[CH:22][CH:23]=3)=[C:11]([CH2:13][C:14]([O:16]CC)=[O:15])[N:12]=2)=[CH:4][CH:3]=1.CO.[OH-].[Na+]>O>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]([C:19]3[O:20][CH:21]=[CH:22][CH:23]=3)=[C:11]([CH2:13][C:14]([OH:16])=[O:15])[N:12]=2)=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 13392283HCID 13392283, compound

Product 1

HCID 13392287HCID 13392287, compoundYield 55.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.0 g of ethyl 2-[2-(4-methylphenyl)-5-(2-furyl)-4-oxazolyl]acetate, 60 ml of methanol, 10 ml of water and 1.5 g of sodium hydroxide are treated in the same manner as described in Example 16. 2.0 g of 2-[2-(4-methylphenyl)-5-(2-furyl)-4-oxazolyl]acetic acid are thereby obtained. Yield: 55.6%

Sources & evidence

ORD record
ord-6843effa6bb6482a80dd2b94104dc51f
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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