3-Nitrophenol → 1-(4-Bromo-benzyloxy)-3-nitro-benzene

HRID 2358777Notes

Reaction equation

HRID 2358777 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[Br:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16]Br)=[CH:14][CH:13]=1>>[Br:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][O:10][C:6]2[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 111373-NitrophenolHCID 685274-Bromobenzyl bromide

Product 1

HCID 603731101-(4-Bromo-benzyloxy)-3-nitro-benzeneYield 97%

Procedure

3-Nitro-phenol (1.00 g, 7.189 mmol) was treated with 4-bromo-benzyl bromide (1.976 g, 7.90 mmol) following the procedure of 189a providing the tile compound (2.1 g, 97%).

Sources & evidence

ORD record
ord-9368800f5d104e74b9e3546c59a92384
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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