Methanol → HCID 13392288, compound

HRID 235878Notes

Reaction equation

HRID 235878 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]([C:20]3[O:21][CH:22]=[CH:23][CH:24]=3)=[C:12]([CH2:14][C:15]([O:17]CC)=[O:16])[N:13]=2)=[CH:5][CH:4]=1.CO.[OH-].[K+]>O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[O:10][C:11]([C:20]3[O:21][CH:22]=[CH:23][CH:24]=3)=[C:12]([CH2:14][C:15]([OH:17])=[O:16])[N:13]=2)=[CH:7][CH:8]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 13392281HCID 13392281, compound

Product 1

HCID 13392288HCID 13392288, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.0 g of ethyl 2-[2-(4-methoxyphenyl)-5-(2-furyl)-4-oxazolyl]acetate, 30 ml of methanol, 3 ml of water and 0.85 g of potassium hydroxide are treated in the same manner as described in Example 16. 1.5 g of 2-[2-(4-methoxyphenyl)-5-(2-furyl)-4-oxazolyl]acetic acid are thereby obtained. Yield: 82.0%

Sources & evidence

ORD record
ord-e591f7ac689040d6a6add273c5985c1a
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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