Methanol → HCID 13392299, compound

HRID 235879Notes

Reaction equation

HRID 235879 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([C:19]3[CH:23]=[CH:22][O:21][CH:20]=3)=[C:11]([CH2:13][C:14]([O:16]CC)=[O:15])[N:12]=2)=[CH:4][CH:3]=1.CO.[OH-].[K+]>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([C:19]3[CH:23]=[CH:22][O:21][CH:20]=3)=[C:11]([CH2:13][C:14]([OH:16])=[O:15])[N:12]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 13361431HCID 13361431, compound

Product 1

HCID 13392299HCID 13392299, compoundYield 87.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1.5 g of ethyl 2-[2-(4-chlorophenyl)-5-(3-furyl)-4-oxazolyl]acetate, 40 ml of methanol, 5 ml of water and 1.5 g of potassium hydroxide are treated in the same manner as described in Example 16. 1.2 g of 2-[2-(4-chlorophenyl)-5-(3-furyl)-4-oxazolyl]acetic acid are thereby obtained. Yield: 87.6%

Sources & evidence

ORD record
ord-682e7408b2e34069b719503386ce59f7
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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