Stannous Chloride → HCID 26189305, compound

HRID 2358798Notes

Reaction equation

HRID 2358798 reaction equation
[CH3:1][O:2][C:3](=[O:21])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[N+:18]([O-])=O)[CH:5]=1.Cl[Sn]Cl>>[CH3:1][O:2][C:3](=[O:21])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[NH2:18])[CH:5]=1

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 9112126HCID 9112126, compound

Product 1

HCID 26189305HCID 26189305, compoundYield 95.4%

Procedure

The product from Example 208a (7.20 g, 23.40 mmol) was reduced with SnCl2 (13.310 g, 70.20 mmol) following the procedure from Example 1f to give the title compound (6.2 g, 95%).

Sources & evidence

ORD record
ord-ee444d13c4db4e8596c0f33a1e747097
Source dataset
uspto-grants-2010_07
Patent number
US07763731B2

Reaction notes

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