Methanol → HCID 13392300, compound

HRID 235880Notes

Reaction equation

HRID 235880 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]([C:20]3[CH:24]=[CH:23][O:22][CH:21]=3)=[C:12]([CH2:14][C:15]([O:17]CC)=[O:16])[N:13]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].CO.[OH-].[K+]>O>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]([C:20]3[CH:24]=[CH:23][O:22][CH:21]=3)=[C:12]([CH2:14][C:15]([OH:17])=[O:16])[N:13]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

5

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 13392298HCID 13392298, compound

Product 1

HCID 13392300HCID 13392300, compoundYield 81.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

7.0 g of ethyl 2-[2-(3,4-dichlorophenyl)-5-(3-furyl)-4-oxazolyl]acetate, 70 ml of methanol, 7 ml of water and 2.0 g of potassium hydroxide are treated in the same manner as described in Example 16. 5.25 g of 2-[2-(3,4-dichlorophenyl)-5-(3-furyl)-4-oxazolyl]acetic acid are thereby obtained. Yield: 81.0%

Sources & evidence

ORD record
ord-8f66ff161491436bb3b27f6259a00d0d
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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