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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2358814Generated: October 27, 2026

2-Nitro-4-trifluoromethyl-biphenyl → 4-(Trifluoromethyl)[1,1′-biphenyl]-2-amine

https://huagongshe.com/reaction/2358814

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Nitro-4-trifluoromethyl-biphenylHCID 11300119—
ReactantTetrahydrofuran ethanolHCID 21873804—
SolventEthanolHCID 702—
Product4-(Trifluoromethyl)[1,1′-biphenyl]-2-amineHCID 11736526—

Reaction Steps

The product from Example 218a was reacted as described in Example 212c substituting 3:1 THF/EtOH (4 mL) for ethanol to give the title amine in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07763731B2
Source datasetuspto-grants-2010_07
ORD IDord-6fd15d2183684f49a534a52cfe8b6b77
Source noteuspto-grants-2010_07