Methanol → HCID 13392290, compound

HRID 235882Notes

Reaction equation

HRID 235882 reaction equation
[CH:1]([C:4]1[O:5][C:6]([C:15]2[O:16][CH:17]=[CH:18][CH:19]=2)=[C:7]([CH2:9][C:10]([O:12]CC)=[O:11])[N:8]=1)([CH3:3])[CH3:2].CO.[OH-].[K+]>O>[CH:1]([C:4]1[O:5][C:6]([C:15]2[O:16][CH:17]=[CH:18][CH:19]=2)=[C:7]([CH2:9][C:10]([OH:12])=[O:11])[N:8]=1)([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 13773146HCID 13773146, compound

Product 1

HCID 13392290HCID 13392290, compoundYield 67.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5.0 g of ethyl 2-[2-isopropyl-5-(2-furyl)-4-oxazolyl]acetate, 70 ml of methanol, 7 ml of water and 3.75 g of potassium hydroxide are treated in the same manner as described in Example 16. 3.0 g of 2-[2-isopropyl-5-(2-furyl)-4-oxazolyl]acetic acid are obtained. Yield: 67.1%

Sources & evidence

ORD record
ord-e45ffc2706134aff899ca9ea719f8b82
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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