Methanol → HCID 13392292, compound

HRID 235883Notes

Reaction equation

HRID 235883 reaction equation
[CH2:1]([C:5]1[O:6][C:7]([C:16]2[O:17][CH:18]=[CH:19][CH:20]=2)=[C:8]([CH2:10][C:11]([O:13]CC)=[O:12])[N:9]=1)[CH2:2][CH2:3][CH3:4].CO.[OH-].[K+]>O>[CH2:1]([C:5]1[O:6][C:7]([C:16]2[O:17][CH:18]=[CH:19][CH:20]=2)=[C:8]([CH2:10][C:11]([OH:13])=[O:12])[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 13773145HCID 13773145, compound

Product 1

HCID 13392292HCID 13392292, compoundYield 83.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.0 g of ethyl 2-[2-n-butyl-5-(2-furyl)-4-oxazolyl]acetate, 50 ml of methanol, 5 ml of water and 4.75 g of potassium hydroxide are treated in the same manner as described in Example 16. 3.0 g of 2-[2-n-butyl-5-(2-furyl)-4-oxazolyl]acetic acid are thereby obtained. Yield: 83.3%

Sources & evidence

ORD record
ord-7b032c366ab849c29f91b0b1162adbc6
Source dataset
uspto-grants-1987_02
Patent number
US04642313

Reaction notes

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