Potassium Carbonate → N-{4-[2-Amino-4-(2-methyl-allyloxy)-phenylsulfanyl]-phenyl}-acetamide

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	3-Bromo-2-methyl-1-propene	HCID 357785	—
Reactant	N-[4-(2-Amino-4-hydroxy-phenylsulfanyl)-phenyl]-acetamide	HCID 67250701	—
Solvent	Dimethylformamide	HCID 6228	—
Product	N-{4-[2-Amino-4-(2-methyl-allyloxy)-phenylsulfanyl]-phenyl}-acetamide	HCID 68460644	100%

Reaction Steps

A mixture of the product from Example 232b (56 mg, 0.17 mmol), 2-methyl-3-bromo propene (20 mg, 0.17 mmol) and potassium carbonate (26 mg, 0.19 mmol) in DMF (1 mL) was stirred at room temperature 15 hr. The next day, the reaction mixture was poured onto ice and the solid collected by filtration providing the title compound (55 mg, 100%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07763731B2
Source dataset	uspto-grants-2010_07
ORD ID	ord-0686f2b3e734465481f32c612d238e4f
Source note	uspto-grants-2010_07