3-Chloroaniline → 3-(3-Chlorophenylamino)-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carbonitrile

関与物質

反応手順

The title compound was prepared from 3-chloroaniline (115 mg, 0.9 mmol) following the method described for the compound of Example 18 to give the product as a pale yellow solid (125 mg). δH (CDCl3) 7.67-7.58 (3H, m), 7.44-7.41 (2H, m), 7.39 (1H, d, J 9.7 Hz), 7.31-7.26 (1H, m), 7.12-7.09 (1H, m), 7.04 (1H, t, J 2.0 Hz), 6.95-6.92 (1H, m), 6.57 (1H, d, J 9.7 Hz), 6.54 (1H, bs). LCMS (ES+) 378 (M+H)+ 35Cl, 380 (M+H)+ 37Cl.

情報源と証拠