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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2358941Generated: October 25, 2026

8-Quinolinol, 5-(chloromethyl)-, hydrochloride (1:1) → Hla-20

https://huagongshe.com/reaction/2358941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Quinolinol, 5-(chloromethyl)-, hydrochloride (1:1)HCID 12269596—
Reactant1-(2-Propynyl)piperazineHCID 14627369—
ProductHla-20HCID 6918819—

Reaction Steps

The title compound was prepared by reaction of 5-chloromethyl-8-hydroxyquinolinoline (A2) with N-propargyl piperazine as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08685955B2
Source datasetuspto-grants-2014_04
ORD IDord-03866808fd904a1ca9179c06a7e440cf
Source noteuspto-grants-2014_04