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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 235896Generated: October 31, 2026

4-Methylbenzoyl Chloride → N-[2-(Furan-2-yl)-2-oxoethyl]-4-methylbenzamide

https://huagongshe.com/reaction/235896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylbenzoyl ChlorideHCID 13405—
ReactantSodium BicarbonateHCID 516892—
Reactant2-Amino-1-(furan-2-yl)ethan-1-one--hydrogen chloride (1/1)HCID 13226138—
ProductN-[2-(Furan-2-yl)-2-oxoethyl]-4-methylbenzamideHCID 1377312483.3%

Reaction Steps

8.0 g of (2-furylcarbonyl)methylamine hydrochloride, 10.5 g of sodium bicarbonate and 9.2 g of 4-methylbenzoyl chloride are treated in the same manner as described in Preparation 1-(1). 10.0 g of N-(4-methylbenzoyl)-(2-furylcarbonyl)methylamine are thereby obtained. Yield: 83.3%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04642313
Source datasetuspto-grants-1987_02
ORD IDord-8d22d7d18eee4aa8a35bbf5c74299548
Source noteuspto-grants-1987_02