HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → Ethyl β-(acetylamino)-γ-oxo-2-furanbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-[2-(Furan-2-yl)-2-oxoethyl]acetamide | HCID 13773126 | — |
| Product | Ethyl β-(acetylamino)-γ-oxo-2-furanbutanoate | HCID 13773136 | 41% |
Reaction Steps
2.6 g of N-acetyl-(2-furylcarbonyl)methylamine, 0.74 g of 61% sodium hydride and 2.9 g of ethyl bromoacetate are treated in the same manner as described in Preparation 1-(2). 1.6 g of ethyl 3-acetylamino-3-(2-furylcarbonyl)propionate are thereby obtained. Yield: 41%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642313 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-cf7a9daec9664351b0543f3116ef2ab9 |
| Source note | uspto-grants-1987_02 |