HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 4-amino-N-(2-hydroxyethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | Benzocaine | HCID 2337 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-amino-N-(2-hydroxyethyl)benzamide | HCID 458761 | — |
Reaction Steps
165.2 parts of ethyl p-aminobenzoate are dissolved in 150 parts of ethanolamine and ethanol is then distilled off at 160° C. The volatile constituents are subsequently stripped off in vacuo and the resulting residue is recrystallised from isopropanol. p-Aminobenzoic acid β-hydroxyethylamide of melting point 116° C. is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642322 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-5be6442ada034df399d693b6e062e945 |
| Source note | uspto-grants-1987_02 |