HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Isopropoxyphenyl)-2-methoxyacetic acid → 1-(4-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-(4-isopropoxyphenyl)-2-methoxyethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Isopropoxyphenyl)-2-methoxyacetic acid | HCID 58432042 | — |
| Reactant | 4-(4-Bromo-3,5-dimethoxyphenyl)oxazole | HCID 58432125 | — |
| Reactant | 2-(4-Isopropoxyphenyl)-N,2-dimethoxy-N-methylacetamide | HCID 86657501 | — |
| Product | 1-(4-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-(4-isopropoxyphenyl)-2-methoxyethanone | HCID 58432052 | — |
| Product | 2-(4-Isopropoxyphenyl)-N,2-dimethoxy-N-methylacetamide | HCID 86657501 | — |
Reaction Steps
2-(4-Isopropoxyphenyl)-N,2-dimethoxy-N-methylacetamide was synthesized from 2-(4-isopropoxyphenyl)-2-methoxyacetic acid following the method used for the synthesis of Example 1. 1-(4-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-(4-isopropoxyphenyl)-2-methoxyethanone was synthesized from 2-(4-isopropoxyphenyl)-N,2-dimethoxy-N-methylacetamide and 4-(4-bromo-3,5-dimethoxyphenyl)oxazole following the method used for the synthesis of Example 7. MS: m/z 490.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685975B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-b3edd4a042c04813a2c641d5776233d9 |
| Source note | uspto-grants-2014_04 |