HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide → 1-(5-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide | HCID 58431993 | — |
| Reactant | 5-(4-Bromo-3,5-dimethoxyphenyl)oxazole | HCID 58432150 | — |
| Product | 1-(5-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone | HCID 58432139 | — |
Reaction Steps
1-(5-(4-Bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone was prepared from 5-(4-bromo-3,5-dimethoxyphenyl)oxazole and N,2-dimethoxy-N-methyl-2-(4-morpholinophenyl)acetamide according to the procedure used in Example 30. Recrystallization from EtOAc gave the product as a yellow solid (0.308 g, 56% yield). MS: m/z 517.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685975B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-383d312c885442fb941f27cedfb94447 |
| Source note | uspto-grants-2014_04 |