HCID 58154811, compound → HCID 58154764, compound

Participants

Reaction Steps

To a solution of tert-butyl 3-(3-nitrophenoxy)pyrrolidine-1-carboxylate (8.73 g, 28.3 mmol) in methanol (50 mL) was added Raney Nickel (1.0 g). The solution was stirred over H2 atmosphere (1 atm) 18 hours. The mixture was filtered, concentrated and purified by chromatography to obtain tert-butyl 3-(3-aminophenoxy)pyrrolidine-1-carboxylate as a white solid (5.47 g, 70% yield)

Provenance & Evidence