2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 58154662, compound

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Reaction Steps

A mixture of methyl 2-(pyridin-3-yl)-1,2,3,4-tetrahydroquinazoline-8-carboxylate (4.0 g, 14.8 mmol) and DDQ (5.0 g, 22.2 mmol) in CH2Cl2 (50 mL) was stirred at room temperature for 24 hours. The solvent was removed in vacuo, and the residue was purified by silica gel column chromatography (5% methanol in CH2Cl2) to obtain methyl 2-(pyridin-3-yl)quinazoline-8-carboxylate (3.5 g, 89% yield).

Provenance & Evidence