4-Bromophenetole → HCID 68416088, compound

HRID 2359475Notes

Reaction equation

HRID 2359475 reaction equation
[CH3:1][C:2]1[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[C:6]([CH3:16])[N:5]=[C:4]([O:17][CH2:18][C:19]([N:21]([CH3:28])[CH:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)=[O:20])[N:3]=1.[C:29]1(Br)[CH:34]=[CH:33][C:32]([O:35][CH2:36][CH3:37])=[CH:31][CH:30]=1>>[CH3:16][C:6]1[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:12])[CH3:13])=[C:2]([CH3:1])[N:3]=[C:4]([O:17][CH2:18][C:19]([N:21]([CH3:28])[CH:22]2[CH2:23][CH2:24][N:25]([C:29]3[CH:34]=[CH:33][C:32]([O:35][CH2:36][CH3:37])=[CH:31][CH:30]=3)[CH2:26][CH2:27]2)=[O:20])[N:5]=1

Participants

3

Reactant 2

HCID 685234-BromophenetoleHCID 59336171Tert-butyl 4,6-dimethyl-2-(2-(methyl(piperidine-4-yl)amino)-2-oxoethoxy)pyrimidine-5-ylcarbamate

Product 1

HCID 68416088HCID 68416088, compound

Procedure

The title compound was synthesized from Compound 31 and phenetyl bromide in the same manner as in Example 32.

Sources & evidence

ORD record
ord-6ded133e71784ec29987e003d2bd62b5
Source dataset
uspto-grants-2014_04
Patent number
US08685989B2

Reaction notes

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