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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2359477Generated: October 31, 2026

Acetyl chloride → Tert-butyl 2-(2-((1-acetylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

https://huagongshe.com/reaction/2359477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantTert-butyl 4,6-dimethyl-2-(2-(methyl(piperidine-4-yl)amino)-2-oxoethoxy)pyrimidine-5-ylcarbamateHCID 59336171—
ProductTert-butyl 2-(2-((1-acetylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamateHCID 59336126—

Reaction Steps

The title compound was synthesized from Compound 31 and acetyl chloride in the same manner as in Example 32.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08685989B2
Source datasetuspto-grants-2014_04
ORD IDord-8603ba5f50f74e93b20ccdf2c078f43b
Source noteuspto-grants-2014_04