4-Fluorobenzoyl chloride → HCID 59336121, compound
Reaction equation
[CH3:1][C:2]1[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[C:6]([CH3:16])[N:5]=[C:4]([O:17][CH2:18][C:19](=[O:27])[NH:20][CH:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)[N:3]=1.[F:28][C:29]1[CH:37]=[CH:36][C:32]([C:33](Cl)=[O:34])=[CH:31][CH:30]=1>>[F:28][C:29]1[CH:37]=[CH:36][C:32]([C:33]([N:24]2[CH2:25][CH2:26][CH:21]([NH:20][C:19](=[O:27])[CH2:18][O:17][C:4]3[N:3]=[C:2]([CH3:1])[C:7]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:12])[CH3:13])=[C:6]([CH3:16])[N:5]=3)[CH2:22][CH2:23]2)=[O:34])=[CH:31][CH:30]=1Participants
3
Procedure
The title compound was synthesized from Compound 57 and 4-fluorobenzoyl chloride in the same manner as in Example 32.
Sources & evidence
- ORD record
- ord-e0a72d3c80cd411ea481253ba49c7bc6
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08685989B2
Reaction notes
Loading…