HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-benzyl-N-methylpiperidin-4-amine → 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-benzyl-N-methylpiperidin-4-amine | HCID 4136128 | — |
| Reactant | Ethyl 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)acetate | HCID 59336100 | — |
| Product | 2-(5-amino-4,6-diisopropylpyrimidine-2-yloxy)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide | HCID 59336117 | — |
Reaction Steps
As in Example 11, a carboxylic acid derivative was synthesized from Compound 13. Then, the title compound was synthesized from the obtained carboxylic acid derivative and 1-benzyl-N-methylpiperidine-4-amine in the same manner as in Example 49.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08685989B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-def4db4d92cc4fe3852948235cd45d50 |
| Source note | uspto-grants-2014_04 |